Immunomodulation in colorectal cancer: disappointment or promise?

Bose-einstein Condensation of Excitons: Promise and Disappointment

The Bose-Einstein condensation of excitons has a long history with seminal contributions from Leonid V. Keldysh. Despite numerous efforts, however, a compelling experimental evidence is still missing. A brief survey of attempts to realize exciton condensation in different semiconductor systems is given. Specific problems compared with atomic Bose condensation are highlighted. More details are g...

Mutual Learning or Mutual Disappointment

The Promise of Biomarkers in Colorectal Cancer Detection

Reducing the burden from death and suffering due to cancer requires improving prevention and treatment efforts and incorporating early detection and risk assessment strategies into clinical practice. Early detection and screening of cancer predates a formal cancer prevention intervention studies. For example, social scientists have been involved in research determining the epidemiologic basis o...

Stool DNA Testing for Colorectal Cancer Shows Promise

Setting and participants. National Institutes of Health– supported trial with industry involvement that included 4482 adults in communities surrounding 22 participating regional and academic health systems in the United States. Participants were asymptomatic, aged 50 to 80 years, and deemed to be at average risk for colorectal cancer. Exclusion criteria included structural colorectal evaluation...

Role of Molecular Biomarkers in Colorectal Cancer

Colorectal cancer (CRC) is amongst the most widespread cancers and is a most common cause of cancer associated mortality universally. Since previous decades, it has been cleared that CRC develops owing to the buildup of a series of genetic and epigenetic changes in the normal colonic epithelium. Regardless of the current development in surgery and therapies, overall survival of end stage CRC pa...